Patients were identified in Ghana’s southern Ashanti region, but only after they had died – raising fears of broader transmission. The virus is transmitted to people via fruit bats, and spreads between humans through direct contact with the bodily fluids of infected people.
However,
according to recent news two people have died in Ghana after contracting a
highly contagious Ebola-like virus, sparking a rush to identify potential
contacts and squash the outbreak before it spreads.
It is the
first time the country has reported cases of Marburg virus, a haemorrhagic
fever with a death rate of up to 88 per cent, and only the second outbreak in
West Africa.
“An
outbreak of a filovirus such as Marburg is always a serious concern, especially
in a setting that hasn’t managed outbreaks before, and when cases are diagnosed
post-mortem,” said Dr Tom Fletcher, an infectious disease consultant at the
Royal Liverpool University hospital.
“Whilst
Marburg probably doesn’t transmit as easily as Ebola, delayed diagnosis often
means that healthcare workers have been exposed and it's likely there would be
cases. We also don’t have as many tools in the cupboard in terms of
diagnostics, treatments and vaccines compared to Ebola,” he told the Telegraph.
Marburg
virus was first identified in 1967 during two epidemics that occurred
concurrently in Marburg and Frankfurt in Germany, and in Belgrade, Serbia. The
outbreak was linked to laboratory work using African green monkeys imported
from Uganda.
In the
decades since, sporadic epidemics have been identified in countries including
Uganda, the Democratic Republic of the Congo and Kenya. The largest outbreak to
date was in Angola in 2005, when 374 caught the virus and 329 died – a fatality
rate of 88 per cent.
Last year,
in the first outbreak to hit West Africa, Guinea also reported one case.
Although 170 contacts were monitored, the virus did not spread more broadly.
The World
Health Organization said the two patients in Ghana had symptoms including
diarrhoea, fever, nausea and vomiting. Samples have been sent to the Institute
Pasteur in Senegal, a WHO Collaborating Centre, to confirm the diagnosis.
The UN
agency added late on Thursday that it will send an emergency team to Ghana to
try and prevent a serious outbreak.
“We are
working closely with the country to ramp up detection, track contacts, be ready
to control the spread of the virus,” said Dr Francis Kasolo, WHO representative
in Ghana.
The
Marburg virus is a top concern for public health officials who are worried
about the next pandemic. It has the potential to cause serious public health
emergencies but there are currently no vaccines or antiviral treatments
approved to treat the virus.
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